Matrix‐assisted laser desorption/ionization (MALDI) is a soft ionization technique used in mass spectrometry for the non‐chromatographic analysis of biopolymers (e.g, proteins, peptides and carbohydrates) and large organic molecules (e.g, polymers, dendrimers). Analytes are embedded in a matrix which absorbs energy at the wavelength of the laser to facilitate vaporization and ionization.
The AB Voyager–DE BioSpectrometry Workstation is a matrix‐assisted laser desorption time‐of‐flight mass spectrometer (MALDI–TOF MS) with a mass range of 500 to approximately 300,000 Da. It is equipped with a pulsed ultraviolet nitrogen laser (337nm, 3 ns pulse, 20 Hz maximum firing rate), a time‐of‐flight mass analyzer with a 1.2 m linear flight path. The instrument can be operated in delayed extraction mode.
Data acquisition and processing is controlled by the Voyager Control Panel and spectra can be analyzed using DataExplorer.