Richard R. Hahin

associate professor emeritus

Representative Publications

Hahin, R. (2010).  “Action potential production: An ion channel dependent process” IN Action Potential: Biophysical and Cellular Context, Initiation and Phases and Propagation. (Cell Biology Research Progress)  M.L. DuBois  (ed.) Nova Science Publishers, Inc. Chapter 4. 33 pages (pagination not known at this time).

Hahin, R, J. Larsen and K. Gasser. 2008. Predictions of the ED50 for action potential block for aliphatic solutes. J. Membrane Biol. 221:2 73-85.

Hahin, R., Z.-Y Chen, G. Reddy, and Y.-M Li. Isolation, purification and N-terminal sequencing of a bioactive peptide that alters action potentials form the venom of Buthus martensii Karsch. Natural Toxins. In press.

Kondratiev, A., and R. Hahin. 2001. ED50 GNa block predictions for phenyl substituted and unsubstituted n-alkanols. J. Membrane Biology 180:123-136.

Hahin, R. and A. Kondratiev. 2001. ED50 AP block predictions for phenyl substituted and unsubstituted n-alkanols. J. Membrane Biology 180:137-145.

Chen, Z.-Y, G. Reddy and R. Hahin. 2000. The isolation and purification of two peptides from the venom of Buthus martensii Karsch. Toxicon 38:1817-1832.

Hahin, R., Z.Y. Chen and G. Reddy. 2000. The isolation and characterization of a peptide that alters Na channels from Buthus martensii Karsch. Toxicon 38:645-660. 

Kondratiev, A. and R. Hahin. Predictions of the AP blocking potency of a series of n-alkanols and their phenyl-substituted counterparts. In preparation.

Hahin, R. and A. Kondratiev. Predictions of sodium channel blocking potency of a series of n-alkanols and their phenyl-substituted counterparts. In preparation. 

Larsen, J., K. Gasser, and R. Hahin. 1996. An analysis of dimethylsulfoxide-induced action potential block: A comparison study of DMSO and other water soluble solutes. Toxicology and Applied Pharmacology 140:296-314.

Borneman, J., Hahin, R. Purification of two protein toxins from Leiurus quinquestriatus venom that specfically modify Na channels. Toxicon 31:1019-1038; 1993. 

Hahin, R., Wang, G.-K., Shapiro, B.I., Strichartz, G. Alterations in sodium channel gating produced by the venom of the marine mollusc Conus striatus. Toxicon. 29:245-259; 1991. 

Hahin, R. Kinetic evidence for two sodium channels in frog skeletal muscle. J. Biological Physics. 17:193-211; 1990. 

Hahin, R. Na activation delays and their relation to inactivation in frog skeletal muscle. J. of Membrane Biology. 118:233-242; 1990. 

Hahin, R. Rate of opening of a population of Na channels in frog skeletal muscle fibers. J. Biological Physics. 17:75-94; 1989. 

Hahin, R. Removal of inactivation causes time-invariant sodium current decays. J. of Gen. Physiol. 92:331-350; 1988. 

Hahin, R. Two open states or two different Na channels in skeletal muscle fibers: Markov models of the decay of na currents in frog skeletal muscle. J. Biological Physics. 16:81-92; 1988.

Campbell, D.T., Hahin, R. Altered sodium and gating current kinetics in frog skeletal muscle caused by low extracellular pH. J. Gen. Physiol. 84:771-788; 1984. 

Hahin, R., Campbell, D.T. Simple shifts in the voltage dependence of Na channel gating caused by divalent cations. J. Gen. Physiol. 82:785-806;1983. 

Hahin, R., Strichartz, G. Effects of deuterium oxide on the rate and dissociation constants for saxitoxin and tetrodotoxin action. J. Gen. Physiol. 78:113-139; 1981.

 

Degrees

Ph.D., 1977, University of Maryland 

B.S., 1968, Michigan State University 

Fields of Interest: Biophysics; Nerve and muscle physiology

Contact:
Richard R. Hahin
hahin@niu.edu